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Non-White Participants Matter in White Matter Disease Studies: The Importance of Diversity in Multiple Sclerosis Clinical Trials

Hamilton, Roy Hoshi; Ciccarelli, Olga; (2022) Non-White Participants Matter in White Matter Disease Studies: The Importance of Diversity in Multiple Sclerosis Clinical Trials. Neurology , 98 (9) pp. 345-346. 10.1212/WNL.0000000000013224. Green open access

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Abstract

For many years, multiple sclerosis (MS) was believed to be a disease seen almost solely in White people. However, mounting evidence has made it clear that non-White individuals are equally, if not more frequently and severely, affected by MS than their White counterparts.1,2 Perhaps both a contributor to and consequence of this racial myth is the fact that non-White persons with MS are dramatically underrepresented in MS clinical trials. There is a pressing need to evaluate whether clinical trials are reflective of the diverse population that is affected by MS.

Type: Article
Title: Non-White Participants Matter in White Matter Disease Studies: The Importance of Diversity in Multiple Sclerosis Clinical Trials
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1212/WNL.0000000000013224
Publisher version: https://doi.org/10.1212/WNL.0000000000013224
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10145516
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