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The Impact of Ethnicity on The Trajectory of Depression Symptom Change During Psychological Interventions

Teo, Celeste WanYee; (2021) The Impact of Ethnicity on The Trajectory of Depression Symptom Change During Psychological Interventions. Doctoral thesis (D.Clin.Psy), UCL (University College London). Green open access

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Abstract

Uncovering variations in depression symptom change across ethnic groups during psychological intervention could improve understanding of differences in treatment response. This study aimed to: (1) identify trajectories of change in treatment; (2) ascertain if depression symptom trajectories varied between BAME and White populations; (3) investigate if sociodemographic and treatment variables predicted association with the identified trajectories; and (4) examine if ethnic groups predicted different trajectory memberships. Adults (N = 17109) with depression and recorded ethnicity were included in the analysis. Depressive symptoms were measured using the Patient Health Questionnaire-9, and co-occurring anxiety was measured using the Generalised Anxiety Disorder-7. Growth Mixture Modelling (GMM) was employed to identify trajectories of symptom change, and multinomial logistic regressions were used to identify ethnicity and other pre-treatment variables associated with trajectory membership. GMM resulted in three depression trajectories of change and four anxiety trajectories. There was a high proportion of patients who did not respond to treatment. Pre-treatment variables that predicted Non-response were: ethnic minority, unemployment, deprived areas, prescribed medications, higher baseline anxiety and depression scores, and long-term physical health conditions. Asian patients had higher odds than White patients associated with trajectories that had high severity for both outcome measures. Black, Other, Mixed-heritage, and Chinese populations were no different from White populations in depressive treatment responses after adjusting for an index of multiple deprivations (IMD). Results have implications for identifying patients at risk of non-response such that clinicians can tailor culturally sensitive interventions for ethnic minority patients.

Type: Thesis (Doctoral)
Qualification: D.Clin.Psy
Title: The Impact of Ethnicity on The Trajectory of Depression Symptom Change During Psychological Interventions
Event: University CollegeLondon
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Copyright © The Author 2021. Original content in this thesis is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10135909
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