Macdonald, CM;
Sridhar, S;
Do, HTX;
Luna-Labrador, J;
Adel, M;
Da Silva, A;
(2021)
Controlling the optical pathlength in continuous-wave reflectance spectroscopy using polarization.
Biomedical Optics Express
, 12
(7)
pp. 4401-4413.
10.1364/BOE.426627.
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Abstract
We investigate potential improvements of continuous-wave diffuse reflectance spectroscopy within highly scattering media by employing polarization gating. Simulations are used to show the extent at which the effective optical pathlength varies in a typical scattering medium as a function of the optical wavelength, the total level of absorption, and the selected polarization channels, including elliptical and circular polarization channels. Experiments then demonstrate that a wavelength dependent polarization gating scheme may reduce the prior knowledge required to solve the problem of chromophore quantification. This is achieved by finding combinations of polarization channels which have similar effective optical pathlengths through the medium at each wavelength.
| Type: | Article |
|---|---|
| Title: | Controlling the optical pathlength in continuous-wave reflectance spectroscopy using polarization |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/BOE.426627 |
| Publisher version: | https://doi.org/10.1364/BOE.426627 |
| Language: | English |
| Additional information: | Copyright © 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement (https://doi.org/10.1364/OA_License_v1#VOR-OA). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10134961 |
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