Fitzsimons, E;
Moulton, V;
Hughes, DA;
Neaves, S;
Ho, K;
Hemani, G;
Timpson, N;
... Ring, S; + view all
(2022)
Collection of genetic data at scale for a nationally representative population: the UK Millennium Cohort Study.
Longitudinal and Life Course Studies
, 13
(1)
pp. 169-187.
10.1332/175795921x16223668101602.
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Abstract
A DNA bank has been created from the Millennium Cohort Study (MCS) saliva samples. A total of 23,336 samples are available, from 9,259 cohort members (4,630 males and 4,629 females), 8,898 mothers and 5,179 fathers. There are 4,533 mother, child, father ‘triads’. This paper describes the collection of the saliva samples from cohort members and their biological parents in the MCS. It analyses response rates and predictors of response, and details the DNA extraction, genotyping and imputation procedures performed on the data.
Type: | Article |
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Title: | Collection of genetic data at scale for a nationally representative population: the UK Millennium Cohort Study |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1332/175795921x16223668101602 |
Publisher version: | https://doi.org/10.1332/175795921X16223668101602 |
Language: | English |
Additional information: | This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions. |
Keywords: | Millennium Cohort Study; ethnic diversity; genetic data; longitudinal; nationally representative population |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Social Research Institute |
URI: | https://discovery.ucl.ac.uk/id/eprint/10131405 |
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