Elbadawi, M;
McCoubrey, LE;
Gavins, FKH;
Ong, JJ;
Goyanes, A;
Gaisford, S;
Basit, AW;
(2021)
Disrupting 3D printing of medicines with machine learning.
Trends in Pharmacological Sciences
10.1016/j.tips.2021.06.002.
(In press).
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Abstract
3D printing (3DP) is a progressive technology capable of transforming pharmaceutical development. However, despite its promising advantages, its transition into clinical settings remains slow. To make the vital leap to mainstream clinical practice and improve patient care, 3DP must harness modern technologies. Machine learning (ML), an influential branch of artificial intelligence, may be a key partner for 3DP. Together, 3DP and ML can utilise intelligence based on human learning to accelerate drug product development, ensure stringent quality control (QC), and inspire innovative dosage-form design. With ML's capabilities, streamlined 3DP drug delivery could mark the next era of personalised medicine. This review details how ML can be applied to elevate the 3DP of pharmaceuticals and importantly, how it can expedite 3DP's integration into mainstream healthcare.
| Type: | Article |
|---|---|
| Title: | Disrupting 3D printing of medicines with machine learning. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.tips.2021.06.002 |
| Publisher version: | https://doi.org/10.1016/j.tips.2021.06.002 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | 3D Printed drug products and formulations, Industry 4.0 and digital health, additive manufacturing, biomedical engineering and pharmaceutical sciences, personalized oral drug delivery systems and medical devices, translational pharmaceutics |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10131387 |
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