Rapetto, F;
Taliotis, D;
Chen, Q;
Ttofi, I;
Iacobazzi, D;
Madeddu, P;
Stoica, SC;
... Caputo, M; + view all
(2021)
Allogeneic Mesenchymal Stromal Cell Injection to Alleviate Ischemic Heart Failure Following Arterial Switch Operation.
JACC: Case Reports
, 3
(5)
pp. 724-727.
10.1016/j.jaccas.2021.02.039.
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Abstract
Cell therapy is a promising tool to prevent and treat heart failure in congenital heart disease. We report the first case of intramyocardial injection of allogeneic mesenchymal stromal cells as rescue therapy in a neonate with ischemic heart failure following arterial switch procedure for isolated transposition of the great arteries. (Level of Difficulty: Advanced.)
| Type: | Article |
|---|---|
| Title: | Allogeneic Mesenchymal Stromal Cell Injection to Alleviate Ischemic Heart Failure Following Arterial Switch Operation. |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.jaccas.2021.02.039 |
| Publisher version: | https://doi.org/10.1016/j.jaccas.2021.02.039 |
| Language: | English |
| Additional information: | © 2021 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY license (http://creativecommons. org/licenses/by/4.0/). |
| Keywords: | CHD, congenital heart disease, FAC, fractional area change, GLS, global longitudinal strain, LCA, left coronary artery, LV, left ventricular, MSC, mesenchymal stromal cell, acute heart failure, coronary vessel anomaly, transposition of the great arteries |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10129756 |
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