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Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?

Daedelow, LS; Banaschewski, T; Berning, M; Bokde, ALW; Bruehl, R; Quinlan, EB; Curran, HV; ... Heinz, A; + view all (2021) Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults? Schizophrenia Research , 228 pp. 271-279. 10.1016/j.schres.2021.01.002. Green open access

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Abstract

Objective: To assess changes in cannabis use in young adults as a function of psychotic-like experiences. Method: Participants were initially recruited at age 14 in high schools for the longitudinal IMAGEN study. All measures presented here were assessed at follow-ups at age 19 and at age 22, respectively. Perceived stress was only assessed once at age 22. Ever users of cannabis (N = 552) gave qualitative and quantitative information on cannabis use and psychotic-like experiences using the Community Assessment of Psychic Experiences (CAPE). Of those, nearly all n = 549 reported to have experienced at least one psychotic experience of any form at age 19. Results: Mean cannabis use increased from age 19 to 22 and age of first use of cannabis was positively associated with a change in cannabis use between the two time points. Change in cannabis use was not significantly associated with psychotic-like experiences at age 19 or 22. In exploratory analysis, we observed a positive association between perceived stress and the experience of psychotic experiences at age 22. Conclusion: Age of first use of cannabis influenced trajectories of young cannabis users with later onset leading to higher increase, whereas the frequency of psychotic-like experiences was not associated with a change in cannabis use. The observed association between perceived stress and psychotic-like experiences at age 22 emphasizes the importance of stress experiences in developing psychosis independent of cannabis use.

Type: Article
Title: Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.schres.2021.01.002
Publisher version: http://dx.doi.org/10.1016/j.schres.2021.01.002
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Cannabis use, Psychotic-like experiences, Age of first use, Perceived stress, Cannabis discontinuation hypothesis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/10129082
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