Macdonald, CM;
Munro, PRT;
(2021)
Approximate image synthesis in optical coherence tomography.
Biomedical Optics Express
, 12
(6)
pp. 3323-3337.
10.1364/boe.420992.
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Abstract
Full-wave models of OCT image formation, which are based on Maxwell’s equations, are highly realistic. However, such models incur a high computational cost, particularly when modelling sample volumes consistent with those encountered in practice. Here, we present an approximate means of synthesizing volumetric image formation to reduce this computational burden. Instead of performing a full-wave scattered light calculation for each A-scan, we perform a full-wave scattered light calculation for a normally incident plane wave only. We use the angular spectrum field representation to implement beam focussing and scanning, making use of an assumption similar to the tilt optical memory effect, to approximately synthesize volumetric data sets. Our approach leads to an order of magnitude reduction in the computation time required to simulate typical B-scans. We evaluate this method by comparing rigorously and approximately evaluated point spread functions and images of highly scattering structured samples for a typical OCT system. Our approach also reveals new insights into image formation in OCT.
| Type: | Article |
|---|---|
| Title: | Approximate image synthesis in optical coherence tomography |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/boe.420992 |
| Publisher version: | https://doi.org/10.1364/BOE.420992 |
| Language: | English |
| Additional information: | © The Optical Society 2021.Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10128460 |
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