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Loneliness and Risk for Cardiovascular Disease: Mechanisms and Future Directions

Paul, E; Bu, F; Fancourt, D; (2021) Loneliness and Risk for Cardiovascular Disease: Mechanisms and Future Directions. Current Cardiology Reports , 23 (6) , Article 68. 10.1007/s11886-021-01495-2. Green open access

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Abstract

PURPOSE OF REVIEW: In this review, we synthesise recent research on the association between loneliness and cardiovascular disease (CVD). We present evidence for mechanisms underlying this association and propose directions for future research. RECENT FINDINGS: Loneliness is related to increased risk of early mortality and CVD comparable to other well-established risk factors such as obesity or smoking. Loneliness has been linked to higher rates of incident CVD, poorer CVD patient outcomes, and early mortality from CVD. Loneliness likely affects risk for these outcomes via health-related behaviours (e.g. physical inactivity and smoking), biological mechanisms (e.g. inflammation, stress reactivity), and psychological factors (e.g. depression) to indirectly damage health.

Type: Article
Title: Loneliness and Risk for Cardiovascular Disease: Mechanisms and Future Directions
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s11886-021-01495-2
Publisher version: http://doi.org/10.1007/s11886-021-01495-2
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Cardiovascular disease, Epidemiology, Health policy, Health promotion, Loneliness
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery.ucl.ac.uk/id/eprint/10128227
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