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Small-molecule inhibitors of carboxylesterase Notum

Zhao, Y; Jolly, S; Benvegnu, S; Jones, EY; Fish, P; (2021) Small-molecule inhibitors of carboxylesterase Notum. FUTURE MEDICINAL CHEMISTRY , 13 (11) 10.4155/fmc-2021-0036. Green open access

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Type: Article
Title: Small-molecule inhibitors of carboxylesterase Notum
Open access status: An open access version is available from UCL Discovery
DOI: 10.4155/fmc-2021-0036
Keywords: Science & Technology, Life Sciences & Biomedicine, Chemistry, Medicinal, Pharmacology & Pharmacy, activity-based protein profiling, fragment screening, high-throughput screening, hit-finding strategies, Notum inhibitors, structural biology, virtual screening, Wnt signaling, STRUCTURAL BASIS, BONE-FORMATION, ENZYME NOTUM, WNT, PROTEIN, TRANSPORT, ACYLATION
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/10127302
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