Kapli, P;
Flouri, T;
Telford, MJ;
(2021)
Systematic errors in phylogenetic trees.
Current Biology
, 31
(2)
R59-R64.
10.1016/j.cub.2020.11.043.
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Abstract
The effort to reconstruct the tree of life was revolutionized by the use of sequences of proteins and nucleic acids. Phylogenetic trees are now routinely inferred using hundreds of thousands of amino acid or nucleotide characters. It thus seems surprising that many aspects of the tree of life are still controversial; conflicting results between large scale phylogenomic studies show that errors remain common despite large datasets. These errors often result from systematic biases in the way sequences evolve. While the resulting systematic errors are well understood, it requires careful efforts to reduce their effects.
Type: | Article |
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Title: | Systematic errors in phylogenetic trees |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.cub.2020.11.043 |
Publisher version: | http://dx.doi.org/10.1016/j.cub.2020.11.043 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
URI: | https://discovery.ucl.ac.uk/id/eprint/10120708 |
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