Eldrid, C;
Thalassinos, K;
(2020)
Developments in tandem ion mobility mass spectrometry.
Biochemical Society Transactions
, 48
(6)
pp. 2457-2466.
10.1042/BST20190788.
Preview |
Text
bst-2019-0788c.pdf - Published Version Download (1MB) | Preview |
Abstract
Ion Mobility (IM) coupled to mass spectrometry (MS) is a useful tool for separating species of interest out of small quantities of heterogenous mixtures via a combination of m/z and molecular shape. While tandem MS instruments are common, instruments which employ tandem IM are less so with the first commercial IM-MS instrument capable of multiple IM selection rounds being released in 2019. Here we explore the history of tandem IM instruments, recent developments, the applications to biological systems and expected future directions.
| Type: | Article |
|---|---|
| Title: | Developments in tandem ion mobility mass spectrometry |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1042/BST20190788 |
| Publisher version: | https://doi.org/10.1042/BST20190788 |
| Language: | English |
| Additional information: | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | ion mobility, mass spectrometry, protein structure, tandem ion mobility |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10118348 |
Archive Staff Only
 |
View Item |
