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Optical coherence tomography (OCT) in neuro-ophthalmology

Minakaran, N; de Carvalho, ER; Petzold, A; Wong, SH; (2021) Optical coherence tomography (OCT) in neuro-ophthalmology. Eye , 35 pp. 17-32. 10.1038/s41433-020-01288-x. Green open access

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Abstract

Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is playing an increasing role in the routine assessment and management of patients with neuro-ophthalmic conditions. Its ability to characterise the optic nerve head, peripapillary retinal nerve fibre layer and cellular layers of the macula including the ganglion cell layer enables qualitative and quantitative assessment of optic nerve disease. In this review, we discuss technical features of OCT and OCT-based imaging techniques in the neuro-ophthalmic context, potential pitfalls to be aware of, and specific applications in more common neuro-ophthalmic conditions including demyelinating, inflammatory, ischaemic and compressive optic neuropathies, optic disc drusen and raised intracranial pressure. We also review emerging applications of OCT angiography within neuro-ophthalmology.

Type: Article
Title: Optical coherence tomography (OCT) in neuro-ophthalmology
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41433-020-01288-x
Publisher version: https://doi.org/10.1038/s41433-020-01288-x
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10118000
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