Mandal, S; Barnett, J; Brill, SE; Brown, JS; Denneny, EK; Hare, SS; Heightman, M; ... ARC Study Group, .; + view all Mandal, S; Barnett, J; Brill, SE; Brown, JS; Denneny, EK; Hare, SS; Heightman, M; Hillman, TE; Jacob, J; Jarvis, HC; Lipman, MCI; Naidu, SB; Nair, A; Porter, JC; Tomlinson, GS; Hurst, JR; ARC Study Group, .; - view fewer (2020) 'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19. Thorax 10.1136/thoraxjnl-2020-215818. (In press).

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Abstract

Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough and 69% fatigue. 14.6% had depression. In those discharged with elevated biomarkers, 30.1% and 9.5% had persistently elevated d-dimer and C reactive protein, respectively. 38% of chest radiographs remained abnormal with 9% deteriorating. Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.

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