Harbers, MC;
de Kroon, AM;
Boer, JMA;
Asselbergs, FW;
Geleijnse, JM;
Verschuren, WMM;
van der Schouw, YT;
(2020)
Adherence to the Dutch dietary guidelines and 15-year incidence of heart failure in the EPIC-NL cohort.
European Journal of Nutrition
, 59
pp. 3405-3413.
10.1007/s00394-019-02170-7.
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Abstract
Purpose: A healthy diet may contribute to the primary prevention of heart failure (HF), but evidence is still inconclusive. We aimed to study the association between adherence to the Dutch dietary guidelines and incidence of HF. Methods: We studied 37,468 participants aged 20–70 years and free of HF at baseline from the EPIC-NL cohort. At baseline (1993–1997), data were collected on demographics, lifestyle, and presence of chronic diseases. Dietary intake was assessed using a 178-item validated food frequency questionnaire. Dietary intake data were used to calculate scores on the Dutch Healthy Diet 2015 Index (DHD15-index) measuring adherence to the Dutch dietary guidelines. The DHD15-index is based on the average daily intake of 14 food groups resulting in a total score ranging between 0 and 140, with higher scores indicating better adherence. HF morbidity and mortality during follow-up were ascertained through linkage with national registries. Cox proportional hazards analysis was used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the association between DHD15 adherence and HF risk, adjusting for sociodemographic and lifestyle characteristics. Results: The average score on the DHD15-index was 71 (SD = 15). During a median follow-up of 15.2 years (IQR 14.1–16.5), 674 HF events occurred. After adjustment for demographic and lifestyle characteristics, higher scores on the DHD15-index were associated with lower risk of HF (HRQ4vsQ1 0.73; 95% CI 0.58–0.93; Ptrend 0.001). Conclusion: In a large Dutch population of middle-aged adults, higher adherence to the Dutch dietary guidelines was associated with lower risk of HF.
| Type: | Article |
|---|---|
| Title: | Adherence to the Dutch dietary guidelines and 15-year incidence of heart failure in the EPIC-NL cohort |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s00394-019-02170-7 |
| Publisher version: | https://doi.org/10.1007/s00394-019-02170-7 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Dietary patterns, Heart failure, Dutch Healthy Diet 2015 Index, Dutch dietary guidelines |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10104999 |
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