Carlson, Eva Ingrid; (1995) A study of voice quality in a group of irradiated laryngeal cancer patients tumour stages T1 and T2. Doctoral thesis (Ph.D), UCL (University College London).

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Abstract

This is a longitudinal study of voice quality in a group of 35 patients irradiated for early vocal fold tumours, stages T1 and T2. Electrolaryngograph (ELG) based analyses were used to obtain objective measurements of speaking fundamental frequency parameters over a wide range of time intervals following radiotherapy. Lx waveforms were also analysed. Perceptual evaluation of voice quality and patients' self assessments of their experience of vocal symptoms and limitations in vocal function after radiotherapy, were carried out. The relationship between perceptual and self assessment parameters and objective voice quality measurements was determined. A few patients underwent periods of voice therapy. A comparison is made of their voice measurements before and after therapy intervention with a group of patients, who did not receive voice therapy. The findings in this study show that, contrary to some early reports that the voice returns to normal in the majority of patients after radiotherapy, most patients' show evidence of residual abnormal voice quality and symptoms as measured and as rated by clinicians and by patients themselves. The majority of patients do not consider these a major problem, however. Evidence is presented of the beneficial effect of voice therapy to help patients compensate for the inevitable tissue damage caused by radiotherapy to the larynx. Electrolaryngograph generated objective measures and Lx waveforms proved sensitive, reliable and clinically applicable for objective voice analysis.

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