Slator, PJ;
Ho, A;
Bakalis, S;
Jackson, L;
Chappell, LC;
Alexander, DC;
Hajnal, JV;
... Hutter, J; + view all
(2021)
Anisotropy in the Human Placenta in Pregnancies Complicated by Fetal Growth Restriction.
In: Özarslan, E and Schultz, T and Zhang, E and Fuster, A, (eds.)
Anisotropy Across Fields and Scales. Mathematics and Visualization.
(pp. pp. 263-276).
Springer: Cham, Switzerland.
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Abstract
The placenta has a unique structure, which enables the transfer of oxygen and nutrients from the mother to the developing fetus. Abnormalities in placental structure are associated with major complications of pregnancy; for instance, changes in the complex branching structures of fetal villous trees are associated with fetal growth restriction. Diffusion MRI has the potential to measure such fine placental microstructural details. Here, we present in-vivo placental diffusion MRI scans from controls and pregnancies complicated by fetal growth restriction. We find that after 30 weeks’ gestation fractional anisotropy is significantly higher in placentas associated with growth restricted pregnancies. This shows the potential of diffusion MRI derived measures of anisotropy for assessing placental function during pregnancy.
| Type: | Proceedings paper |
|---|---|
| Title: | Anisotropy in the Human Placenta in Pregnancies Complicated by Fetal Growth Restriction |
| ISBN-13: | 9783030562144 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-3-030-56215-1_13 |
| Publisher version: | https://doi.org/10.1007/978-3-030-56215-1_13 |
| Language: | English |
| Additional information: | © The Author(s) 2021 Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence and indicate if changes were made. The images or other third party material in this chapter are included in the chapter's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the chapter's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10102896 |
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