Dimitriadis, A;
Tsang, Y;
Thomas, RAS;
Palmer, AL;
Eaton, D;
Lee, J;
Patel, R;
... Clark, CH; + view all
(2020)
Μulti-institutional dosimetric delivery assessment of intracranial stereotactic radiosurgery on different treatment platforms.
Radiotherapy and Oncology
, 147
pp. 153-161.
10.1016/j.radonc.2020.05.024.
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Nisbet_Μulti-institutional dosimetric delivery assessment of intracranial stereotactic radiosurgery on different treatment platforms_AAM.pdf - Accepted Version Download (2MB) | Preview |
Abstract
BACKGROUND AND PURPOSE: Assessment of dosimetric accuracy of radiosurgery on different treatment platforms. MATERIAL AND METHODS: Thirty-three single fraction treatment plans were assessed at thirty centres using an anthropomorphic head phantom with target and brainstem structures. The target being a single irregular shaped target, ∼8cc, 10 mm from the brainstem. The phantom was "immobilised", scanned, planned and treated following the local protocols. EBT-XD films and alanine pellets were used to measure absolute dose, inside both the target and the brainstem, and compared with TPS predicted dose distributions. RESULTS: PTV alanine measurements from gantry-based linacs showed a median percentage difference to the TPS of 0.65%. Cyberknife (CK) had the highest median difference of 2.3% in comparison to the other platforms. GammaKnife (GK) showed the smallest median of 0.3%. Similar trends were observed in the OAR with alanine measurements showing median percentage differences of1.1%, 2.0% and 0.4%, for gantry-based linacs, CK and GK respectively. All platforms showed comparable gamma passing rates between axial and sagittal films. CONCLUSIONS: This comparison has highlighted the dosimetric variation between measured and TPS calculated dose for each delivery platforms.. The results suggest that clinically acceptable agreement with the predicted dose distributions is achievable by all treatment delivery systems. Radiosurgery, Dosimetry, End-to-end, Audit, Anthropomorphic Phantom, Alanine, Radiochromic film.
| Type: | Article |
|---|---|
| Title: | Μulti-institutional dosimetric delivery assessment of intracranial stereotactic radiosurgery on different treatment platforms |
| Location: | Ireland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.radonc.2020.05.024 |
| Publisher version: | https://doi.org/10.1016/j.radonc.2020.05.024 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| Keywords: | Radiosurgery, Dosimetry, Audit, Anthropomorphic phantom, Alanine, Radiochromic film |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10100155 |
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