Petzold, A;
Wattjes, MP;
Costello, F;
Flores-Rivera, J;
Fraser, CL;
Fujihara, K;
Leavitt, J;
... Plant, GT; + view all
(2014)
The investigation of acute optic neuritis: a review and proposed protocol.
Nature Reviews Neurology
, 10
pp. 447-458.
10.1038/nrneurol.2014.108.
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Abstract
Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple sclerosis (MS) at some point during their disease course. Differentiation of acute episodes of MS-associated optic neuritis from other autoimmune and inflammatory optic neuropathies is vital for treatment choice and further patient management, but is not always straightforward. Over the past decade, a number of new imaging, laboratory and electrophysiological techniques have entered the clinical arena. To date, however, no consensus guidelines have been devised to specify how and when these techniques can be most rationally applied for the diagnostic work-up of patients with acute optic neuritis. In this article, we review the literature and attempt to formulate a consensus for the investigation of patients with acute optic neuritis, both in standard care and in research with relevance to clinical treatment trials.
| Type: | Article |
|---|---|
| Title: | The investigation of acute optic neuritis: a review and proposed protocol |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/nrneurol.2014.108 |
| Publisher version: | https://doi.org/10.1038/nrneurol.2014.108 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Diagnostic markers, Eye manifestations, Multiple sclerosis, Prognostic markers |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10098004 |
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