Ahmed, J;
Gultekinoglu, M;
Edirisinghe, M;
(2020)
Bacterial cellulose micro-nano fibres for wound healing applications.
Biotechnology Advances
, 41
, Article 107549. 10.1016/j.biotechadv.2020.107549.
Preview |
Text
Edirisinghe_JBA-D-20-00094_R1.pdf - Accepted Version Download (3MB) | Preview |
Abstract
Bacterial cellulose (BC) is cellulose produced by a few limited species of bacteria in given conditions. BC has many remarkable properties such as its high mechanical properties, water uptake ability and biocompatibility which makes it a very desirable material to be used for wound healing. Inherently due to these important properties, the material is very resistant to easy processing and thus difficult to produce into useful entities. Additionally, being rate limited by the dependency on bacterial production, high yield is difficult to obtain and thus secondary material processing is sought after. In this review, BC is explained in terms of synthesis, structure and properties. These beneficial properties are directly related to the material's great potential in wound healing where it has also been trialled commercially but ultimately failed due to processing issues. However, more recently there has been increased frequency in scientific work relating to BC processing into hybrid polymeric fibres using common laboratory fibre forming techniques such as electrospinning and pressurised gyration. This paper summarises current progress in BC fibre manufacturing, its downfalls and also gives a future perspective on how the landscape should change to allow BC to be utilised in wound care in the current environment.
| Type: | Article |
|---|---|
| Title: | Bacterial cellulose micro-nano fibres for wound healing applications |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.biotechadv.2020.107549 |
| Publisher version: | https://doi.org/10.1016/j.biotechadv.2020.107549 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Bacterial cellulose, Fibre production, Fibres, Gluconacetobacter xylinum, Wound healing |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10096282 |
Archive Staff Only
 |
View Item |
