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Minimally invasive photoacoustic imaging: Current status and future perspectives

Zhao, T; Desjardins, AE; Ourselin, S; Vercauteren, T; Xia, W; (2019) Minimally invasive photoacoustic imaging: Current status and future perspectives. Photoacoustics , 16 , Article 100146. 10.1016/j.pacs.2019.100146. Green open access

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Abstract

Photoacoustic imaging (PAI) is an emerging biomedical imaging modality that is based on optical absorption contrast, capable of revealing distinct spectroscopic signatures of tissue at high spatial resolution and large imaging depths. However, clinical applications of conventional non-invasive PAI systems have been restricted to examinations of tissues at depths less than a few cm due to strong light attenuation. Minimally invasive photoacoustic imaging (miPAI) has greatly extended the landscape of PAI by delivering excitation light within tissue through miniature fibre-optic probes. In the past decade, various miPAI systems have been developed with demonstrated applicability in several clinical fields. In this article, we present an overview of the current status of miPAI and our thoughts on future perspectives.

Type: Article
Title: Minimally invasive photoacoustic imaging: Current status and future perspectives
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.pacs.2019.100146
Publisher version: https://doi.org/10.1016/j.pacs.2019.100146
Language: English
Additional information: © 2019 The Authors. Published by Elsevier GmbH. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Photoacoustic imaging, Photoacoustic computed tomography, Photoacoustic microscopy, Multi-modal imaging, Minimally invasive procedures, Interventional photoacoustic imaging, Photoacoustic endoscopy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10093963
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