Novel therapeutic targets in epilepsy: oxidative stress and iron metabolism

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Novel therapeutic targets in epilepsy: oxidative stress and iron metabolism

Li, Y-F; Thom, M; Jacques, TS; (2020) Novel therapeutic targets in epilepsy: oxidative stress and iron metabolism. Neuropathology and Applied Neurobiology , 46 (6) pp. 519-521. 10.1111/nan.12615. Green open access

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Abstract

Malformations of Cortical Development (MCD) are one of the most frequent causes of multidrug‐resistant focal epilepsy, of which focal cortical dysplasia type IIb (FCDIIb) and Tuberous Sclerosis.

Type:	Article
Title:	Novel therapeutic targets in epilepsy: oxidative stress and iron metabolism
Location:	England
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1111/nan.12615
Publisher version:	https://doi.org/10.1111/nan.12615
Language:	English
Additional information:	This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords:	Nrf-2, Oxidative stress (OS), epilepsy, focal cortical dysplasia type IIb (FCDIIb) and Tuberous Sclerosis complex (TS), iron metabolism
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI:	https://discovery.ucl.ac.uk/id/eprint/10093333

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