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Photoacoustic tomography setup using LED illumination

Leskinen, J; Pulkkinen, A; Tick, J; Tarvainen, T; (2019) Photoacoustic tomography setup using LED illumination. In: Ntziachristos, V and Zemp, R, (eds.) Opto-Acoustic Methods and Applications in Biophotonics IV. SPIE: Washington, USA. Green open access

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Abstract

Photoacoustic tomography (PAT) is a hybrid imaging modality that combines optical contrast with ultrasound resolution. Most of the PAT configurations are based on high-energy solid-state lasers such as Nd:YAG laser. In this work, a PAT system that uses light-emitting diode (LED) as a light source is introduced. The system is designed so that the imaged target can be stationary. The target is illuminated by a LED light source from one side and the pressure wave is measured using an acoustic transducer that is rotated around the target. Image reconstruction is based on Bayesian approach to illposed inverse problems. The system was tested with light absorbing targets also in limited-view and sparse angle measurement situations. The results show that LED-based instrumentation and advanced reconstruction methods can form a potential PAT system that can also be applied in limited-view and sparse angle photoacoustic tomography.

Type: Proceedings paper
Title: Photoacoustic tomography setup using LED illumination
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany
Location: Munich, GERMANY
Dates: 24 June 2019 - 25 June 2019
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2526723
Publisher version: https://doi.org/10.1117/12.2526723
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: photoacoustic tomography, limited-view measurements, light-emitting diode, LED, inverse problems, Bayesian methods
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: https://discovery.ucl.ac.uk/id/eprint/10092765
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