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Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: Valuable Programming Insights from Anecdotal Observations

Dayal, V; Akram, H; Zrinzo, L; Limousin, P; Foltynie, T; (2020) Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: Valuable Programming Insights from Anecdotal Observations. Stereotactic and Functional Neurosurgery 10.1159/000505701. (In press). Green open access

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Abstract

In this article, we use a case to illustrate and discuss some practically important learning points about programming subthalamic nucleus deep brain stimulation for Parkinson’s disease patients and highlight clinically relevant issues resulting from anatomical and device-related anomalies. These include the phenomenon of a dominant subthalamic nucleus, clinical variability with delayed response to stimulation, equivalence of electrical charge when using short-pulse settings, and issues regarding conversion of settings between constant-current and constant-voltage devices that are increasingly common with the use of device components from multiple manufacturers.

Type: Article
Title: Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: Valuable Programming Insights from Anecdotal Observations
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.1159/000505701
Publisher version: https://doi.org/10.1159/000505701
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10092669
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