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Medicinal Plant Analysis: A Historical and Regional Discussion of Emergent Complex Techniques

Fitzgerald, M; Heinrich, M; Booker, A; (2020) Medicinal Plant Analysis: A Historical and Regional Discussion of Emergent Complex Techniques. Frontiers in Pharmacology , 10 , Article 1480. 10.3389/fphar.2019.01480. Green open access

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Abstract

The analysis of medicinal plants has had a long history, and especially with regard to assessing a plant’s quality. The first techniques were organoleptic using the physical senses of taste, smell, and appearance. Then gradually these led on to more advanced instrumental techniques. Though different countries have their own traditional medicines China currently leads the way in terms of the number of publications focused on medicinal plant analysis and number of inclusions in their Pharmacopoeia. The monographs contained within these publications give directions on the type of analysis that should be performed, and for manufacturers, this typically means that they need access to more and more advanced instrumentation. We have seen developments in many areas of analytical analysis and particularly the development of chromatographic and spectroscopic methods and the hyphenation of these techniques. The ability to process data using multivariate analysis software has opened the door to metabolomics giving us greater capacity to understand the many variations of chemical compounds occurring within medicinal plants, allowing us to have greater certainty of not only the quality of the plants and medicines but also of their suitability for clinical research. Refinements in technology have resulted in the ability to analyze and categorize plants effectively and be able to detect contaminants and adulterants occurring at very low levels. However, advances in technology cannot provide us with all the answers we need in order to deliver high-quality herbal medicines and the more traditional techniques of assessing quality remain as important today.

Type: Article
Title: Medicinal Plant Analysis: A Historical and Regional Discussion of Emergent Complex Techniques
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fphar.2019.01480
Publisher version: https://doi.org/10.3389/fphar.2019.01480
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Science & Technology, Life Sciences & Biomedicine, Pharmacology & Pharmacy, herbal medicine, medicinal plant, analysis, quality, pharmacopoeia, complexity, advances, NEAR-INFRARED SPECTROSCOPY, SUPERCRITICAL-FLUID CHROMATOGRAPHY, GAS-LIQUID-CHROMATOGRAPHY, GEOGRAPHICAL ORIGIN, MASS-SPECTROMETRY, HEART-DISEASE, LICORICE ROOT, EXTRACTION, CONSTITUENTS, FLAVONOIDS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharma and Bio Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10091187
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