Estimation of Timing Resolution for Very Fast Time-Of-Flight Detectors in Monte Carlo Simulations

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Estimation of Timing Resolution for Very Fast Time-Of-Flight Detectors in Monte Carlo Simulations

Efthimiou, N; Emond, E; Cawthorne, C; Tsoumpas, C; Thielemans, K; (2018) Estimation of Timing Resolution for Very Fast Time-Of-Flight Detectors in Monte Carlo Simulations. In: 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC). IEEE: Sydney, Australia. Green open access

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Efthimiou MIC2018 proc - Estimation_of_Timing_Resolution_for_very_fast_Time_Of_Flight_detectors_in_Monte_Carlo_simulations.pdf - Accepted Version
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Abstract

In PET imaging the depth of absorption in the crystal contributes to the detection time uncertainty, which impacts the time resolution of the scatter. In addition, affects the nature of the timing distribution. It was found that when Photon Travel Spread (PTS) in the crystal is the only factor affecting the timing uncertainty, in which case, a Laplace kernel might describe the measured data, more accurately. It was shown that for crystals as thin as 20 mm the RMSE of the Laplace was smaller than that of a Normal. While when PTS is combined with an addition coincidence detection resolution (CDR) then, a Normal achieves better RMSE, but with dependency on the crystal size. Results in terms of CRC, of a simulated NEMA phantom, confirmed that reconstruction using a Laplace kernel can model the data better for thicker crystals.

Type:	Proceedings paper
Title:	Estimation of Timing Resolution for Very Fast Time-Of-Flight Detectors in Monte Carlo Simulations
Event:	2018 IEEE Nuclear Science Symposium and Medical Imaging Conference
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1109/NSSMIC.2018.8824748
Publisher version:	https://doi.org/10.1109/NSSMIC.2018.8824748
Language:	English
Additional information:	This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords:	GATE, STIR, Scintillation Crystals, Time-OfFlight, PET, LYSO
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI:	https://discovery.ucl.ac.uk/id/eprint/10087279