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Fantastic beasts and how to find them—Molecular identification of the mitochondrial ATP-sensitive potassium channel

Davidson, SM; Szabadkai, G; Duchen, MR; (2019) Fantastic beasts and how to find them—Molecular identification of the mitochondrial ATP-sensitive potassium channel. Cell Calcium , 84 , Article 102100. 10.1016/j.ceca.2019.102100. Green open access

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Abstract

Despite reported sightings over many years, certain mitochondrial-specific channels have proven to be elusive beasts, evading molecular identification. However, combining modern genetics with a wave of their ion-sensing wand, researchers have managed to capture first the mitochondrial calcium uniporter, and now that semi-mythological beast, the mitochondrial ATP-sensitive potassium (mitoKATP) channel.

Type: Article
Title: Fantastic beasts and how to find them—Molecular identification of the mitochondrial ATP-sensitive potassium channel
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ceca.2019.102100
Publisher version: https://doi.org/10.1016/j.ceca.2019.102100
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Ischaemia and reperfusion, Katp channel, Mitochondria
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science
URI: https://discovery.ucl.ac.uk/id/eprint/10086205
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