Neshatvar, N;
Damaso, R;
Seifnaraghi, N;
Demosthenous, A;
Bayford, R;
(2019)
Towards a System for Tracking Drug Delivery Using Frequency Excited Gold Nanoparticles.
Sensors
, 19
(21)
, Article 4750. 10.3390/s19214750.
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Abstract
Nanoparticle-based drugs are rapidly evolving to treat different conditions and have considerable potential. A new system based on the combination of electrical impedance tomography (EIT) imaging and a power amplifier with a RF coil has been developed to study the effect of gold nanoparticles (AuNPs) when excited in the MHz frequency range. We show that samples including AuNPs have a temperature increase of 1–1.5 ◦C due to the presence of RF excitation at 13.56 MHz which provides a higher rate of change for solutions without AuNPs. They also show more than a 50% increase in conductivity in difference imaging as the result of this excitation. The change for samples without AuNPs is 40%.
| Type: | Article |
|---|---|
| Title: | Towards a System for Tracking Drug Delivery Using Frequency Excited Gold Nanoparticles |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3390/s19214750 |
| Publisher version: | https://doi.org/10.3390/s19214750 |
| Language: | English |
| Additional information: | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | drug delivery; electrical impedance tomography (EIT); gold nanoparticles; power amplifier; radio frequency (RF) induction |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10085024 |
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