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The impact of digital health technologies on tuberculosis treatment: a systematic review

Ngwatu, BK; Nsengiyumva, NP; Oxlade, O; Mappin-Kasirer, B; Nguyen, NL; Jaramillo, E; Falzon, D; ... Collaborative group on the impact of digital technologies on TB; + view all (2018) The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal , 51 (1) , Article 1701596. 10.1183/13993003.01596-2017. Green open access

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Abstract

Digital technologies are increasingly harnessed to support treatment of persons with tuberculosis (TB). Since in-person directly observed treatment (DOT) can be resource intensive and challenging to implement, these technologies may have the potential to improve adherence and clinical outcomes. We reviewed the effect of these technologies on TB treatment adherence and patient outcomes. We searched several bibliographical databases for studies reporting the effect of digital interventions, including short message service (SMS), video-observed therapy (VOT) and medication monitors (MMs), to support treatment for active TB. Only studies with a control group and which reported effect estimates were included. Four trials showed no statistically significant effect on treatment completion when SMS was added to standard care. Two observational studies of VOT reported comparable treatment completion rates when compared with in-person DOT. MMs increased the probability of cure (RR 2.3, 95% CI 1.6–3.4) in one observational study, and one trial reported a statistically significant reduction in missed treatment doses relative to standard care (adjusted means ratio 0.58, 95% CI 0.42–0.79). Evidence of the effect of digital technologies to improve TB care remains limited. More studies of better quality are needed to determine how such technologies can enhance programme performance.

Type: Article
Title: The impact of digital health technologies on tuberculosis treatment: a systematic review
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1183/13993003.01596-2017
Publisher version: https://doi.org/10.1183/13993003.01596-2017
Language: English
Additional information: This version is distributed under the terms of the Creative Commons Attribution NonCommercial Licence 4.0. https://creativecommons.org/licenses/by-nc/4.0/
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/10077484
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