Nweke, MC;
Rathore, AS;
Bracewell, DG;
(2018)
Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture.
[Editorial comment].
Trends in Biotechnology
, 36
(10)
pp. 992-995.
10.1016/j.tibtech.2018.01.001.
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Abstract
Poor understanding of the events leading to chromatography column aging makes it difficult to monitor column lifetimes. The lack of established procedures in this area has made it difficult to establish industry standards. Therefore, it is important to understand resin aging mechanisms and techniques to monitor column aging during operation.
| Type: | Article |
|---|---|
| Title: | Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.tibtech.2018.01.001 |
| Publisher version: | https://doi.org/10.1016/j.tibtech.2018.01.001 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | chromatography resin aging, chromatography resin lifetime, chromatography resin aging mechanisms, fouling characterisation techniques |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Biochemical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10071098 |
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