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Congenital mesoblastic nephroma 50 years after its recognition: A narrative review

Gooskens, SL; Houwing, ME; Vujanic, GM; Dome, JS; Diertens, T; Coulomb-l'Hermine, A; Godzinski, J; ... van den Heuvel-Eibrink, MM; + view all (2017) Congenital mesoblastic nephroma 50 years after its recognition: A narrative review. [Review]. Pediatric Blood & Cancer , 64 (7) , Article e26437. 10.1002/pbc.26437. Green open access

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Abstract

Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up‐to‐date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment‐related mortality (both surgery‐ and chemotherapy‐related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.

Type: Article
Title: Congenital mesoblastic nephroma 50 years after its recognition: A narrative review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/pbc.26437
Publisher version: https://doi.org/10.1002/pbc.26437
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: congenital mesoblastic nephroma, infancy, clinical characteristics, histology, genetics, treatment, outcome, review, renal tumor
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10070923
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