Titarenko, AV;
Shishkin, SV;
Shcherbakova, LV;
Verevkin, EG;
Holmes, M;
Bobak, M;
Malyutina, SK;
(2018)
Dynamics of cognitive functions in ageing and their relationship to education level = Динамика когнитивных функций при старении и их связь с уровнем образования.
Nevrologiya, Neiropsikhiatriya, Psikhosomatika
, 10
(4)
pp. 46-51.
10.14412/2074-2711-2018-4-46-51.
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Abstract
Age-related cognitive changes in the Russian population have not been sufficiently studied. Objective: to assess the time course of changes in cognitive functions (CF) in two serial measurements 9 years apart in the urban population of middle, elder, and senile age and their relationship to education level. Patients and methods. A random male and female sample of 45-69-year-old Novosibirsk residents (n=9360; HAPIEE project) was surveyed. CF was tested by standard methods. Resurvey was conducted in a random subsample (n=1663) included in this analysis. The mean follow-up period was 8.8 years (SD 1.1). Results and discussion. The test for semantic verbal fluency revealed its dynamic decline in all age groups, which was steeper in women than in men (p<0.001). Persons aged 70 years and older showed negative changes in memory, verbal fluency, and attention (p<0.001). Persons with primary (6%) and vocational (26%) education had steeper rates of decline in delayed recall (p=0.011; 0.038) than those with university education (35%). Conclusion. It is established that a dynamic decrease in CF begins at the age of 55–59 years; it is steeper among those aged 70 years and older. An age-related decline in memory function is accelerated in persons with lower educational levels.
| Type: | Article |
|---|---|
| Title: | Dynamics of cognitive functions in ageing and their relationship to education level = Динамика когнитивных функций при старении и их связь с уровнем образования |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.14412/2074-2711-2018-4-46-51 |
| Publisher version: | https://doi.org/10.4000/tc.495610.14412/2074-2711-... |
| Language: | Russian |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | cognitive functions; age-related changes; cognitive decline; education level |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10070590 |
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