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Iron deficiency anaemia: experiences and challenges

Stelle, I; Kalea, AZ; Pereira, DIA; (2019) Iron deficiency anaemia: experiences and challenges. Proceedings of the Nutrition Society , 78 (1) pp. 19-26. 10.1017/S0029665118000460. Green open access

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Abstract

Iron deficiency remains the largest nutritional deficiency worldwide and the main cause of anaemia. Severe iron deficiency leads to anaemia known as iron deficiency anaemia (IDA), which affects a total of 1·24 billion people, the majority of whom are children and women from resource-poor countries. In sub-Saharan Africa, iron deficiency is frequently exacerbated by concomitant parasitic and bacterial infections and contributes to over 120 000 maternal deaths a year, while it irreparably limits the cognitive development of children and leads to poor outcomes in pregnancy. Currently available iron compounds are cheap and readily available, but constitute a nonphysiological approach to providing iron that leads to significant side effects. Consequently, iron deficiency and IDA remain without an effective treatment, particularly in populations with high burden of infectious diseases. So far, despite considerable investment in the past 25 years in nutrition interventions with iron supplementation and fortification, we have been unable to significantly decrease the burden of this disease in resource-poor countries. If we are to eliminate this condition in the future, it is imperative to look beyond the strategies used until now and we should make an effort to combine community engagement and social science approaches to optimise supplementation and fortification programmes.

Type: Article
Title: Iron deficiency anaemia: experiences and challenges
Location: Royal Coll Phys & Surg, Glasgow, SCOTLAND
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S0029665118000460
Publisher version: http://doi.org/10.1017/S0029665118000460
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Iron deficiency anaemia: Capacity building: Iron supplementation
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Education
URI: https://discovery.ucl.ac.uk/id/eprint/10069997
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