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Accurate Representation of Microscopic Scatterers in Realistic Simulation of OCT Image Formation

Ossowski, P; Curatolo, A; Sampson, DD; Munro, PRT; (2018) Accurate Representation of Microscopic Scatterers in Realistic Simulation of OCT Image Formation. In: 2018 IEEE Photonics Conference (IPC). IEEE Green open access

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Abstract

There is currently much interest in developing OCT image formation models based on Maxwell's equations. However, all such models face a common challenge: how can microscopic scatterers be represented without limiting the overall size of the sample that can be modelled? Here we show how micro-scopic scatterers can be accurately represented on computational grids with cells too large to faithfully represent such scatterers using conventional approaches. We also validate this approach experimentally. This approach to OCT image simulation allows for image formation for biological tissues to be simulated with unprecedented realism.

Type: Proceedings paper
Title: Accurate Representation of Microscopic Scatterers in Realistic Simulation of OCT Image Formation
Event: 2018 IEEE Photonics Conference (IPC), 30 September - 4 October 2018, Reston, VA, USA
ISBN-13: 9781538653586
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/IPCon.2018.8527134
Publisher version: https://doi.org/10.1109/IPCon.2018.8527134
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Refractive index , Biological system modeling , Scattering , Computational modeling , Optical coherence tomography , Optimized production technology , Mathematical model
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10067947
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