Lutz, A;
Klimecki, OM;
Collette, F;
Poisnel, G;
Arenaza-Urquijo, E;
Marchant, NL;
De La Sayette, V;
... Chételat, G; + view all
(2018)
The Age-Well observational study on expert meditators in the Medit-Ageing European project.
Alzheimer's and Dementia: Translational Research and Clinical Interventions
, 4
pp. 756-764.
10.1016/j.trci.2018.11.002.
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Abstract
Introduction: The Age-Well observational, cross-sectional study investigates the affective and cognitive mechanisms of meditation expertise with behavioral, neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's disease (AD). Methods: Thirty cognitively unimpaired individuals aged 65 years or older with at least 10,000 hours of practice in mindfulness meditation (MM) and loving-kindness and compassion meditation (LKCM) are selected. The outcomes are the neuroimaging brain correlates of MM and LKCM and the assessments of long-term meditation practices on behavioral, neural, and biological measures as compared to nonmeditator older controls from the Age-Well randomized controlled trial. Results Recruitment and data collection began in late 2016 and will be completed by late 2019. Discussion: Results are expected to foster the understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying the meditation intervention in the Age-Well randomized controlled trial. These finding will contribute to the design of meditation-based prevention randomized controlled trials for the aged population and to the exploration of the possible long-time developmental trajectory of meditation training.
| Type: | Article |
|---|---|
| Title: | The Age-Well observational study on expert meditators in the Medit-Ageing European project |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.trci.2018.11.002 |
| Publisher version: | https://doi.org/10.1016/j.trci.2018.11.002 |
| Language: | English |
| Additional information: | Copyright © 2018 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| Keywords: | Aging, Alzheimer's disease, Dementia, Prevention, Cognition, Reserve, Meditation expertise, Mindfulness meditation, Compassion and loving-kindness meditation, Emotion, Lifestyle, Neuroimaging, Blood markers, Sleep |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10065791 |
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