Ireland, S;
Martin, ACR;
(2019)
ZincBind - The Database of Zinc Binding Sites.
Database : the Journal of Biological Databases and Curation
, 2019
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Abstract
Zinc is one of the most important biologically active metals. 10% of the human genome is thought to encode a zinc binding protein and its uses encompass catalysis, structural stability, gene expression, and immunity. At present, there is no specific resource devoted to identifying and presenting all currently known zinc binding sites. Here we present ZincBind, a database of zinc binding sites and its web front-end. Using the structural data in the Protein Data Bank, ZincBind identifies every instance of zinc binding to a protein, identifies its binding site, and clusters sites based on 90% sequence identity. There are currently 24,992 binding sites, clustered into 7,489 unique sites. The data are available over the web where they can be browsed and downloaded, and via a REST API. ZincBind is regularly updated and will continue to be updated with new data and features.
| Type: | Article |
|---|---|
| Title: | ZincBind - The Database of Zinc Binding Sites |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | https://doi.org/10.1093/database/baz006 |
| Language: | English |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10065415 |
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