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Imaging of late complications of cancer therapy in children

Shelmerdine, SC; Chavhan, GB; Babyn, PS; Nathan, PC; Kaste, SC; (2017) Imaging of late complications of cancer therapy in children. Pediatric Radiology , 47 (3) pp. 254-266. 10.1007/s00247-016-3708-6. Green open access

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Abstract

Long-term survival after childhood cancer has improved dramatically over recent decades but survivors face lifelong risks of adverse health effects. Many of these chronic conditions are a direct result of previous therapeutic exposures. Compared to their siblings, survivors face a greater than 8-fold increase in relative risk of severe or life-threatening medical conditions; the most significant of these include second malignancies and cardiovascular and pulmonary diseases. Imaging can play a key role in identifying and characterizing such complications, which can be reasonably predicted with knowledge of the child’s treatment. This article highlights the varied radiologic presentations and features seen in late cancer-therapy-related conditions.

Type: Article
Title: Imaging of late complications of cancer therapy in children
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00247-016-3708-6
Publisher version: https://doi.org/10.1007/s00247-016-3708-6
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Cancer therapy, Children, Computed tomography, Late effects, Magnetic resonance imaging, Radiography, Toxicities
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
URI: https://discovery.ucl.ac.uk/id/eprint/10063762
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