Teske, AJ;
Linschoten, M;
Kamphuis, JAM;
Naaktgeboren, WR;
Leiner, T;
van der Wall, E;
Kuball, J;
... Asselbergs, FW; + view all
(2018)
Cardio-oncology: an overview on outpatient management and future developments.
[Review].
Netherlands Heart Journal
, 26
(11)
pp. 521-532.
10.1007/s12471-018-1148-7.
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Abstract
Recent advances in the early detection and treatment of cancer have led to increasing numbers of cancer survivors worldwide. Nonetheless, despite major improvements in the outcome of these patients, long-term side effects of radio- and chemotherapy affect both patient survival and quality of life, independent of the oncological prognosis. Chemotherapy-related cardiac dysfunction is one of the most notorious short-term side effects of anticancer treatment, occurring in ~10% of patients. Progression to overt heart failure carries a strikingly poor prognosis with a 2-year mortality rate of 60%. Early detection of left ventricular damage by periodic monitoring and prompt initiation of heart failure treatment is key in improving cardiovascular prognosis. To meet the growing demand for a specialised interdisciplinary approach for the prevention and management of cardiovascular complications induced by cancer treatment, a new discipline termed cardio-oncology has evolved. However, an uniform, multidisciplinary approach is currently lacking in the Netherlands. This overview provides an introduction and comprehensive summary of this emerging discipline and offers a practical strategy for the outpatient management of this specific patient population.
| Type: | Article |
|---|---|
| Title: | Cardio-oncology: an overview on outpatient management and future developments |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s12471-018-1148-7 |
| Publisher version: | https://doi.org/10.1007/s12471-018-1148-7 |
| Language: | English |
| Additional information: | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Cardiotoxicity, Chemotherapy, Cardio-oncology, Heart failure |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10062551 |
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