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Redistribution of organ specific blood flow in response to food ingestion measured by R-R-interval averaged golden-angle spiral phase contrast MRI

Hauser, J; Muthurangu, V; Taylor, A; Steeden, J; Jones, A; (2016) Redistribution of organ specific blood flow in response to food ingestion measured by R-R-interval averaged golden-angle spiral phase contrast MRI. In: (Proceedings) 19th Annual SCMR Scientific Sessions. Society for Cardiovascular Magnetic Resonance Green open access

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Abstract

Background: The ingestion of food is known to increase mesenteric blood flow significantly. However, it remains unknown whether this increased flow demand to the intestine is compensated by an increase in total cardiac output (CO) alone, or by redistribution of blood flow from other organs, caused by changes in organ-specific vascular resistance. Non-invasive studies on the vascular response of small arteries have been scarce due to technical constraints, as conventional as well as MRI-based methods for non-invasive flow assessment are time-consuming and observer-dependent. We present a novel, comprehensive phenotyping model of the hemodynamic changes caused by the ingestion of a high-energy liquid meal, assessed by novel MRI sequences for the rapid assessment of small vessel blood flow.

Type: Proceedings paper
Title: Redistribution of organ specific blood flow in response to food ingestion measured by R-R-interval averaged golden-angle spiral phase contrast MRI
Event: 19th Annual SCMR Scientific Sessions
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1532-429X-18-S1-O92
Publisher version: https://jcmr-online.biomedcentral.com/articles/10....
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Cardiac Output, Vascular Resistance, Superior Mesenteric Artery, Ventricular Volume, Celiac Artery
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Childrens Cardiovascular Disease
URI: https://discovery.ucl.ac.uk/id/eprint/10060265
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