Krause, K;
Bear, H;
Edbrooke-Childs, J;
Wolpert, M;
(2019)
Review: What Outcomes Count? A Review of Outcomes Measured for Adolescent Depression between 2007 and 2017.
Journal of the American Academy of Child and Adolescent Psychiatry
, 58
(1)
pp. 61-71.
10.1016/j.jaac.2018.07.893.
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Abstract
Objective: Measurement of treatment outcomes in childhood depression has traditionally focused on assessing symptoms from the clinician’s perspective, without exploring other outcome domains or considering young people’s perspectives. This systematic review explored the extent to which multidimensional and multi-informant outcome measurement have been used in clinical research for adolescent depression in the past decade, and how patterns evolved over time. Method: We searched Embase, MEDLINE and PsycINFO, and included studies published between 2007 and 2017 that assessed the effectiveness of treatments or service provision for adolescent depression. Of 7483 studies screened, 95 met inclusion criteria and were included for data extraction and analysis. Results: We identified ten outcomes domains, of which studies assessed two on average, using four outcome measures. Most studies (94%) measured symptoms, followed by functioning (52%). Other domains such as personal growth, relationships, quality of life, or service satisfaction were each considered by less than one in ten studies. Youth self-report was considered by 54% but tended to focus on secondary outcomes. Multidimensional and multi-informant measurement has been more frequent in studies published since 2015. Conclusion: Recent clinical research continues to prioritize symptoms measurement based on clinician report and has not yet fully embraced multi-dimensional and multi-informant approaches. In the context of significant policy shifts towards patient-centered and evidence-based care, measuring what matters most to patients has become a priority, but this is not yet widely reflected in clinical research.
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