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Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing

Wong, JK-H; Todd, MH; Rutledge, PJ; (2017) Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing. Molecules , 22 (2) 10.3390/molecules22020200. Green open access

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Abstract

Small-molecule fluorescent probes play a myriad of important roles in chemical sensing. Many such systems incorporating a receptor component designed to recognise and bind a specific analyte, and a reporter or transducer component which signals the binding event with a change in fluorescence output have been developed. Fluorescent probes use a variety of mechanisms to transmit the binding event to the reporter unit, including photoinduced electron transfer (PET), charge transfer (CT), Förster resonance energy transfer (FRET), excimer formation, and aggregation induced emission (AIE) or aggregation caused quenching (ACQ). These systems respond to a wide array of potential analytes including protons, metal cations, anions, carbohydrates, and other biomolecules. This review surveys important new fluorescence-based probes for these and other analytes that have been reported over the past five years, focusing on the most widely exploited macrocyclic recognition components, those based on cyclam, calixarenes, cyclodextrins and crown ethers; other macrocyclic and non-macrocyclic receptors are also discussed.

Type: Article
Title: Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/molecules22020200
Publisher version: http://dx.doi.org/10.3390/molecules22020200
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: chemosensor, fluorescence sensing, fluoroionophore, molecular probes, spectroscopy, Biosensing Techniques, Crown Ethers, Cyclodextrins, Fluorescent Dyes, Heterocyclic Compounds, Ions, Macrocyclic Compounds, Quantum Dots
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharma and Bio Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10057559
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