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Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015

Pratas, AC; Goldschmidt, P; Lebeaux, D; Aguilar, C; Ermak, N; Benesty, J; Charlier, C; ... Errera, MH; + view all (2018) Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015. Emerging Infectious Diseases , 24 (2) pp. 193-200. 10.3201/eid2402.171167. Green open access

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Abstract

We describe the frequency, demographic and clinical features, and visual outcomes of ocular syphilis infections observed during 2012–2015 at a tertiary reference center in Paris, France. Twenty-one cases (29 eyes) were identified. The occurrence of ocular syphilis increased from 1 case in 2012 to 5 cases in 2013, 6 cases in 2014, and 9 cases in 2015 (2.22–25.21/1,000 individual patients/year for the period). Among case-patients, an annual 20%–33% were co-infected with HIV. Seventy-six percent of ocular syphilis infections occurred in men who have sex with men. Seventy-five percent of case-patients had a good final visual outcome (best-corrected visual acuity >0.3 logMAR score). Visual outcome was worse for HIV-positive patients than for HIV-negative patients (p = 0.0139). At follow-up, the best visual outcomes were observed in patients whose mean time from first ocular symptom to consultation was 15 days (SD +19 days).

Type: Article
Title: Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015
Open access status: An open access version is available from UCL Discovery
DOI: 10.3201/eid2402.171167
Publisher version: http://dx.doi.org/10.3201/eid2402.171167
Language: English
Additional information: © 2018 The Centers for Disease Control and Prevention. Emerging Infectious Diseases is an open access journal in the public domain, its usage policy conforms to conditions set for by Creative Commons (https://creativecommons.org/licenses/by/4.0/).
URI: https://discovery.ucl.ac.uk/id/eprint/10053964
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