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Dynamic contrast enhanced CT in nodule characterization: How we review and report

Qureshi, NR; Shah, A; Eaton, RJ; Miles, K; Gilbert, FJ; (2016) Dynamic contrast enhanced CT in nodule characterization: How we review and report. Cancer Imaging , 16 (1) , Article 16. 10.1186/s40644-016-0074-4. Green open access

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Abstract

Incidental indeterminate solitary pulmonary nodules (SPN) that measure less than 3 cm in size are an increasingly common finding on computed tomography (CT) worldwide. Once identified there are a number of imaging strategies that can be performed to help with nodule characterization. These include interval CT, dynamic contrast enhanced computed tomography (DCE-CT), ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography (¹⁸F-FDG-PET-CT). To date the most cost effective and efficient non-invasive test or combination of tests for optimal nodule characterization has yet to be determined. DCE-CT is a functional test that involves the acquisition of a dynamic series of images of a nodule before and following the administration of intravenous iodinated contrast medium. This article provides an overview of the current indications and limitations of DCE- CT in nodule characterization and a systematic approach to how to perform, analyse and interpret a DCE-CT scan.

Type: Article
Title: Dynamic contrast enhanced CT in nodule characterization: How we review and report
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s40644-016-0074-4
Publisher version: https://doi.org/10.1186/s40644-016-0074-4
Language: English
Additional information: © 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).
Keywords: Dynamic contrast enhanced CT, Solitary pulmonary nodules
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10053867
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