Vos, SB;
Cardoso, MJ;
Wylezinska-Arridge, M;
Thomas, DL;
De Vita, E;
Yiannakas, MC;
Carmichael, DW;
... Ourselin, S; + view all
(2016)
Evaluation of 3D T1-weighted imaging at 3T across scanner vendors and models.
In:
(Proceedings) ISMRM 24th Annual Meeting & Exhibition.
(pp. pp. 4701-4703).
International Society for Magnetic Resonance in Medicine: Singapore.
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Abstract
Volumetric analyses of 3D T1-weighted images has become an integral part of the clinical work-up and research studies. Variation between scanners, in both vendors and models, is a major confound in combining imaging-derived biomarkers across sites. In this work, we analyse test-retest data from di×erent days on six 3 T scanners from three vendors to quantify this inter-scanner variability compared to intra-scanner variability. Contrast-to-noise ratios as well as volumetric analyses are performed showing between-scanner variation in total brain volumes – indicating di×erent scanner calibrations – but also tissue-speciÒc di×erences – possibly arising from di×erent e×ective contrasts.
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