Zhang, Siqi;
(2018)
Functional polymer fibre spinning by infusion gyration.
Doctoral thesis (Ph.D), UCL (University College London).
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Abstract
Fibres show promising applications such as textiles, filtration, sensing and tissue engineering. In this study, an infusion gyration system to produce polymer micro and nano fibres with functions was introduced. By using this method, functional fibres can be formed from polymer solutions mixed with other functional materials. PEO or PVA water solution was used for making the spinning solutions. The fluorescence protein bound with gold nanoparticles was carried by the PEO water solution, from which the fibres assembled with protein were successfully generated through infusion gyration. A mixed molecular weight PVA combined water solution mixed with processed magnetic nanoparticles achieved fabrication of magnetically controllable fibres have the potential for drug release and its demonstration test showed a positive result. This spinning system provides control of the polymer solution flow rate during spinning which affects the fibre morphology such as average diameter and size distribution. The relationship between the spinning parameters and the product properties was studied for better understanding of the method. The analysis of infusion gyration and its fibre forming process was carried out. The fibres were characterised using several methods, such as optical microscopy, SEM, FTIR and UV-Vis, to establish the potential of infusion gyration and to confirm the functions of final fibre product. The infusion gyration system provides a simple micro and nano scale assembly approach to integrate different protein functionalities into nanofibres with potential applications. Magnetic PVA nanofibres are promising for drug delivery.
| Type: | Thesis (Doctoral) |
|---|---|
| Qualification: | Ph.D |
| Title: | Functional polymer fibre spinning by infusion gyration |
| Event: | UCL (University College London) |
| Open access status: | An open access version is available from UCL Discovery |
| Language: | English |
| UCL classification: | UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10052048 |
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