Mumford, E;
Unwin, RJ;
Walsh, SB;
(2018)
Liquorice, Liddle, Bartter or Gitelman—how to differentiate?
Nephrology Dialysis Transplantation
, 34
(1)
pp. 38-39.
10.1093/ndt/gfy199.
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Abstract
Hypokalaemia with alkalosis can suggest excess aldosterone. Aldosterone stimulates the collecting duct mineralocorticoid receptor (MR) to upregulate the epithelial sodium channel (ENaC) and stimulate electrogenic sodium reabsorption, with secretion of potassium and protons. Gitelman, Bartter and Liddle syndrome, and liquorice ingestion all cause hypokalaemic alkalosis. This mini-review outlines the pathophysiology of these conditions as well as how to differentiate them.
| Type: | Article |
|---|---|
| Title: | Liquorice, Liddle, Bartter or Gitelman—how to differentiate? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/ndt/gfy199 |
| Publisher version: | https://doi.org/10.1093/ndt/gfy199 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | hypokalaemia, gitelman, bartter, liddle, liquorice |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10051168 |
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