Howard, LM;
Ryan, EG;
Trevillion, K;
Anderson, F;
Bick, D;
Bye, A;
Byford, S;
... Pickles, A; + view all
(2018)
Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy.
The British Journal of Psychiatry
, 212
(1)
pp. 50-56.
10.1192/bjp.2017.9.
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Abstract
Background: There is limited evidence on the prevalence and identification of antenatal mental disorders. Aims: To investigate 1) prevalence of mental disorders in early pregnancy; 2) diagnostic accuracy of depression-screening (Whooley) questions, compared with the Edinburgh Postnatal Depression Scale (EPDS), against the Structured Clinical Interview DSM-IV-TR. Method: Cross-sectional survey of women responding to Whooley questions asked at first antenatal appointment. Women responding positively and a random sample of women responding negatively were invited to participate. Results: Population prevalence was 27% (95%CI 22-32%): 11% (95%CI 8-14%) depression, 15% (95%CI 11-19%) anxiety disorders, 2% (95%CI 1-4%) obsessive-compulsive disorder, 0.8% (95%CI 0- 1%) PTSD, 2% (95%CI 0.4-3%) eating disorders, 0.03% (95%CI 0-0.2%) bipolar disorder, 0.7% (95%CI 0-1%) borderline personality disorder. For identification of depression, likelihood ratios were 8.2 (Whooley) and 9.8 (EPDS). Diagnostic accuracy was similar in identifying any disorder (likelihood ratios 5.8 and 6). Conclusions: Endorsement of Whooley questions in pregnancy indicates the need for a clinical assessment of diagnosis and could be implemented when maternity professionals have been appropriately trained on how to ask the questions sensitively, in settings where a clear referral and care pathway is available.
| Type: | Article |
|---|---|
| Title: | Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1192/bjp.2017.9 |
| Publisher version: | http://doi.org/10.1192/bjp.2017.9 |
| Language: | English |
| Additional information: | COPYRIGHT: © The Royal College of Psychiatrists 2018 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10048623 |
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