Wang, RJ;
Miller, RF;
Huang, L;
(2017)
Approach to Fungal Infections in Human Immunodeficiency Virus-Infected Individuals Pneumocystis and Beyond.
Clinics in Chest Medicine
, 38
(3)
pp. 465-477.
10.1016/j.ccm.2017.04.008.
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Abstract
Many fungi cause pulmonary disease in HIV-infected patients. Major pathogens include Pneumocystis jirovecii, Cryptococcus neoformans, Aspergillus species, Histoplasma capsulatum, Coccidioides species, Blastomyces dermatitidis, Paracoccidioides brasiliensis, Talaromyces marneffei, and Emmonsia species. Because symptoms are frequently non-specific, a high index of suspicion for fungal infection is required for diagnosis. Clinical manifestations of fungal infection in HIV-infected patients frequently depend on the degree of immunosuppression and the CD4 + TH cell count. Establishing definitive diagnosis is important because treatments differ. Primary and secondary prophylaxis depends on CD4+ TH cell counts as well as geographic location and local prevalence of disease.
| Type: | Article |
|---|---|
| Title: | Approach to Fungal Infections in Human Immunodeficiency Virus-Infected Individuals Pneumocystis and Beyond |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ccm.2017.04.008 |
| Publisher version: | https://doi.org/10.1016/j.ccm.2017.04.008 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Respiratory System, Human immunodeficiency virus, Opportunistic infection, Pneumonia, Mycoses, Pneumocystis, PENICILLIUM-MARNEFFEI INFECTION, BRONCHOALVEOLAR LAVAGE FLUID, CARINII-PNEUMONIA, EMMONSIA-PASTEURIANA, JIROVECII PNEUMONIA, RISK-FACTORS, PULMONARY PARACOCCIDIOIDOMYCOSIS, DISSEMINATED HISTOPLASMOSIS, RADIOGRAPHIC FINDINGS, CLINICAL PRESENTATION |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10044740 |
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