Parker, L;
Mansfield, S;
Sneddon, K;
Charles, B;
Rafiq, Q;
(2017)
Advances and challenges in umbilical cord blood and tissue bioprocessing: procurement and storage.
Cell and Gene Therapy Insights
, 3
(6)
pp. 489-508.
10.18609/cgti.2017.042.
Preview |
Text
2017 Advances and challenges in umbilical cord blood and tissue bioprocessing - procurement and storage (Parker).pdf - Published Version Download (784kB) | Preview |
Abstract
Umbilical cord tissue and blood is banked to complement the rapidly advancing field of tissue engineering and regenerative medicine for both autologous and allogeneic therapeutic applications. Whilst many problems concerning the use of the hematopoietic and multipotential mesenchymal stromal cells contained therein may be addressed through the future development of GMP-compliant manufacturing strategies, collection and bioprocessing of these tissues can be optimised in the present to maximise clinical outcomes. In this review, we describe current procurement, processing and storage approaches for umbilical cord blood and tissue; current challenges and how these may be met to augment translation and use of therapeutics harnessing their derivatives.
| Type: | Article |
|---|---|
| Title: | Advances and challenges in umbilical cord blood and tissue bioprocessing: procurement and storage |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.18609/cgti.2017.042 |
| Publisher version: | https://doi.org/10.18609/cgti.2017.042 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Biochemical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10044401 |
Archive Staff Only
 |
View Item |
