Staples, NA;
Goding, JA;
Gilmour, AD;
Aristovich, KY;
Byrnes-Preston, P;
Holder, DS;
Morley, JW;
... Green, RA; + view all
(2018)
Conductive Hydrogel Electrodes for Delivery of Long-Term High Frequency Pulses.
Frontiers in Neuroscience
, 11
, Article 748. 10.3389/fnins.2017.00748.
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Abstract
Nerve block waveforms require the passage of large amounts of electrical energy at the neural interface for extended periods of time. It is desirable that such waveforms be applied chronically, consistent with the treatment of protracted immune conditions, however current metal electrode technologies are limited in their capacity to safely deliver ongoing stable blocking waveforms. Conductive hydrogel (CH) electrode coatings have been shown to improve the performance of conventional bionic devices, which use considerably lower amounts of energy than conventional metal electrodes to replace or augment sensory neuron function. In this study the application of CH materials was explored, using both a commercially available platinum iridium (PtIr) cuff electrode array and a novel low-cost stainless steel (SS) electrode array. The CH was able to significantly increase the electrochemical performance of both array types. The SS electrode coated with the CH was shown to be stable under continuous delivery of 2 mA square pulse waveforms at 40,000 Hz for 42 days. CH coatings have been shown as a beneficial electrode material compatible with long-term delivery of high current, high energy waveforms.
| Type: | Article |
|---|---|
| Title: | Conductive Hydrogel Electrodes for Delivery of Long-Term High Frequency Pulses |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fnins.2017.00748 |
| Publisher version: | https://doi.org/10.3389/fnins.2017.00748 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Neurosciences, Neurosciences & Neurology, conductive hydrogel, high frequency stimulation, nerve block, neural interfaces, peripheral nerve cuff array |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10042297 |
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